Melanisation of Cryptococcus neoformans in human brain tissue

Authors
Nosanchuk, JD Rosas, AL Lee, SC Casadevall, A
Citation
Jd. Nosanchuk et al., Melanisation of Cryptococcus neoformans in human brain tissue, LANCET, 355(9220), 2000, pp. 2049-2050
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
355
Issue
9220
Year of publication
2000
Pages
2049 - 2050
Database
ISI
SICI code
0140-6736(20000610)355:9220<2049:MOCNIH>2.0.ZU;2-B
Abstract
Melanin-specific reagents revealed melanin in cryptococcal cell walls from human brain tissue, and fungal-cell melanin "ghosts" were recovered from in fected tissue. The results indicate that Cryptococcus neoformans melanises during human infection.