scintimammography (SMM) to have nide clinical use, physicians must be
able to rapidly direct biopsy of small cancers. We therefore undertook
a theoretical and experimental study of lesion visibility vs. acquisi
tion time and tumor size. Theoretical considerations as to acquisition
time and contrast suggested that compression would significantly impr
ove lesion visibility for small cancers. These predictions were confir
med with phantom studies. Patient studies showed that high confidence
images of small primary breast tumors can be produced with the additio
n of breast compression. We conclude that breast compression would imp
rove SMM detection of small primary breast cancers.