Role of zinc ion in translational accuracy becomes crystal clear

Authors
Musier-Forsyth, K Beuning, PJ
Citation
K. Musier-forsyth et Pj. Beuning, Role of zinc ion in translational accuracy becomes crystal clear, NAT ST BIOL, 7(6), 2000, pp. 435-436
Citations number
24
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NATURE STRUCTURAL BIOLOGY
ISSN journal
10728368 → ACNP
Volume
7
Issue
6
Year of publication
2000
Pages
435 - 436
Database
ISI
SICI code
1072-8368(200006)7:6<435:ROZIIT>2.0.ZU;2-S
Abstract
Aminoacyl-tRNA synthetases play a central role in assuring a high degree of accuracy in protein synthesis. New high resolution structures of threonyl- tRNA synthetase bound to threonine or a threonyl-adenylate analog reveal ho w an active site zinc atom contributes to translational fidelity.