Progressive supranuclear palsy

Progressive supranuclear palsy (PSP) or Steele-Richardson-Olszewski syndrom e is a neurodegenerative disease of middle and late age. It is under-diagno sed not only by general physicians but also by neurologists. The cause of P SP is not known. Exposure to toxins and viruses has been proposed in the ae tiology of PSP without any concrete evidence. The features of PSP resemble those of Parkinson's disease and the two diseases are often confused. Corti cobasal degeneration and multisystem atrophy are other differential diagnos es. Despite certain common features with Parkinson's disease, corticobasal degeneration, and mutisystem atrophy, there are important differences that help to differentiate it from these disorders.