Critically injured patients offer an exceptional challenge to intensivists.
Pre-existing disease states complicate horrendous disruptions in normal an
atomy and physiology. The hypermetabolic, catabolic response brought on by
trauma, shock, or sepsis serves to reprioritize the normal nutritional home
ostasis of the body. Appropriate nutritional support not only minimizes the
wasting effects of hypermetabolism but potentially offers additional benef
its. Studies of feeding routes, substrates, and timing suggest that adequat
e support may decrease infectious complications and modulate the metabolic
response. Injured patients are a heterogenous group, making the definition
of adequate support and interpretation of experimental findings difficult.
Ultimately, most severely injured patients need directed nutritional suppor
t because of their inability to ingest nourishment by conventional means. T
his article emphasizes a practical approach to these patients.