Selective N-methylation of pyrazolone with methanol by use of ZrO2 catalyst in the liquid phase

Authors
Shinoda, S Shima, S Yamakawa, T
Citation
S. Shinoda et al., Selective N-methylation of pyrazolone with methanol by use of ZrO2 catalyst in the liquid phase, SYNLETT, (6), 2000, pp. 809-810
Citations number
19
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
6
Year of publication
2000
Pages
809 - 810
Database
ISI
SICI code
0936-5214(200006):6<809:SNOPWM>2.0.ZU;2-Q
Abstract
Selective methylation of pyrazolone to 1-methylpyrazolone was investigated with ZrO2, which is a representative metal oxide with amphoteric character. The high selectivity up to similar to 77% was obtained at 503 K. Mechanism is proposed in view of weak acidic-moderately basic pair sites of ZrO2.