Sequential 1,3-dipolar cycloaddition-Pictet-Spengler reactions. A versatile tactical combination

Authors
Dondas, HA Duraisingham, J Grigg, R MacLachlan, WS MacPherson, DT Thornton-Pett, M Sridharan, V Suganthan, S
Citation
Ha. Dondas et al., Sequential 1,3-dipolar cycloaddition-Pictet-Spengler reactions. A versatile tactical combination, TETRAHEDRON, 56(24), 2000, pp. 4063-4070
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
56
Issue
24
Year of publication
2000
Pages
4063 - 4070
Database
ISI
SICI code
0040-4020(20000609)56:24<4063:S1CRAV>2.0.ZU;2-W
Abstract
The combination of thermal or Ag(I) catalysed imine-->azomethine ylide-->cy cloaddition cascades with a subsequent Pictet-Spengler reaction allows the assembly of polyfunctional N-heterocycles, via formation of 4 bonds and 2 r ings, in good yield. (C) 2000 Elsevier Science Ltd. All rights reserved.