Design and synthesis of multifunctional phospholipids

Authors
Drakopoulou, E Tsivgoulis, GM Mukhopadhyay, A Brisson, A
Citation
E. Drakopoulou et al., Design and synthesis of multifunctional phospholipids, TETRAHEDR L, 41(21), 2000, pp. 4131-4134
Citations number
13
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
41
Issue
21
Year of publication
2000
Pages
4131 - 4134
Database
ISI
SICI code
0040-4039(20000529)41:21<4131:DASOMP>2.0.ZU;2-Z
Abstract
The synthesis of a bifunctionalized phosholipid capable of binding streptav idin or poly-histidine-tagged proteins is reported for the first time. The head group containing both a biotin and an NTA chelator is synthesized via a new approach using solid phase synthesis. (C) 2000 Elsevier Science Ltd. All rights reserved.