L'antiphonaire mobilizes in the weaving of its diegetic content numerous fo
rms of non-literary knowledge. Through an epistemocritical approach, this a
rticle studies one of them: the alchemical knowledge. Not only does it spot
the principal hermetic references in the novel, but it also analyses how t
he borrowing of theories from alchemical philosophy influences Aquin's dieg
esis and writing. It shows primarily how the novel's epigraph, taken from a
n alchemical treatise attributed to Mary the Copt, structures the whole net
work of characters who, far from being distinct individuals, appear as the
various metamorphoses of a unique entity divided between the poles of the c
onscious and of the unconscious. In that case, L'antiphonaire represents th
e attempt to reunite both of these elements through a process in which the
literary work coincides with the Great Work.