Ag. Royse et al., Reduced neuropsychological dysfunction using epiaortic echocardiography and the exclusive Y graft, ANN THORAC, 69(5), 2000, pp. 1431-1438
Citations number
25
Categorie Soggetti
Cardiovascular & Respiratory Systems","Medical Research Diagnosis & Treatment
Background. To examine the effect of screening the aorta for atheroma befor
e aortic manipulation and use of exclusive Y graft revascularization on the
incidence of neuropsychological dysfunction after coronary artery bypass.
Methods. Aortic atheroma was detected using epiaortic and transesophageal e
chocardiography. Atheroma avoidance was facilitated by use of the exclusive
Y graft technique, which has no aortic coronary anastomoses. In the contro
l group aortic atheroma was assessed by manual palpation, and we attempted
to avoid any atheroma detected. In this group we also used aorta-coronary g
rafts. Transcranial Doppler imaging of the right middle cerebral artery was
used to detect cerebral microemboli. Neuropsychological dysfunction was de
fined as a 20% or more decline in score for at least 20% of a neuropsychome
tric battery of ten tests for each patient.
Results. Late dysfunction at 57 +/- 2 days postoperatively in the control g
roup was 38.1% and in the echo/Y group was 3.8% (p' = 0.012). Microemboli d
etected by transcranial Doppler imaging during periods of aortic manipulati
on was greater for those with late dysfunction (5.2 +/- 3.0 compared with 0
.5 +/- 0.2) (p' = 0.018). No clinical strokes occurred in either group.
Conclusions. The combined techniques of epiaortic screening and exclusive Y
graft for coronary artery bypass operations resulted in a low incidence of
late neuropsychological dysfunction.
(C) 2000 by The Society of Thoracic Surgeons.