Methicillin-resistant Staphylococcus aureus (MRSA) infections are an emergi
ng problem in children. The following are 2 case reports of unsuspected MRS
A infections: the first is an infant with cervical adenitis and the second
is a child with a deep infection of the toe. Both patients failed outpatien
t therapy with oral cephalosporins and required hospitalization for surgica
l drainage. Both patients had cultures positive for MRSA at surgery. Neithe
r patient had any risk factors for acquiring MRSA. Thus, outpatients with p
resumed staphylococcal infections who fail oral therapy with cephalosporins
map be infected with MRSA.