Synthesis and in vitro antibacterial activity of 3-[N-methyl-N-(3-methyl-1,3-thiazolium-2-yl)amino]methyl cephalosporin derivatives

Authors
Kim, SH Son, H Nam, G Chi, DY Kim, JH
Citation
Sh. Kim et al., Synthesis and in vitro antibacterial activity of 3-[N-methyl-N-(3-methyl-1,3-thiazolium-2-yl)amino]methyl cephalosporin derivatives, BIOORG MED, 10(11), 2000, pp. 1143-1145
Citations number
18
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
11
Year of publication
2000
Pages
1143 - 1145
Database
ISI
SICI code
0960-894X(20000605)10:11<1143:SAIVAA>2.0.ZU;2-F
Abstract
The new cephalosporins having N-linked quarternary ammonium salt at C-3 pos ition were prepared from the reaction of 2-methylimino-3-methyl-1,3-thiazol ine derivatives with cephalosporins. Also antimicrobial activities of those compounds were determined. (C) 2000 Elsevier Science Ltd. All rights reser ved.