The purpose of this study was to evaluate the pain experience of women duri
ng mammography for breast cancer screening. Possible associations with pers
onal and medical history, sociodemographics and/or situational factors were
studied. It was also investigated whether this pain influenced the intenti
on to return for future breast cancer screening. In the Netherlands, women
between 50-75 years are invited for screening every two years. A total of 1
200 participants were asked to fill up a questionnaire. The response rate w
as 79.5% (n = 954), and 945 questionnaires contained adequate information f
or analyses. A total of 689 women (72.9%) described mammography as mild to
severely painful. In this group, compared to the group that reported no pai
n, the following factors occurred significantly more often: sensitive breas
ts (P = 0.001), family history of breast diseases (P = 0.017), expected pai
n based on former mammography (P = 0.001), high education (P = 0.008), anxi
ety (P = 0.001), breast sensitivity in last three days (P = 0.001), insuffi
cient attention of technologist (P = 0.001). Other factors like age, hormon
al status, breast size and hormone use were not associated with the pain ex
perienced. Thirty-two women (3.3%) indicated that they would not attend fur
ther screening, 25 (2.6%) reported that the pain might deter them, six wome
n (0.6%) had other reasons, one woman (0.1%) was sure not to come because o
f severe pain. In conclusion, a large majority of women attending breast ca
ncer screening describes mammography as painful (72.9%). Factors associated
with pain were described. Relatively few women (2.7%) indicated that the p
ain might deter them from future mammography. Recommendations are given to
reduce the pain experienced during screening mammography.