Eating disorders in adolescent females with and without type 1 diabetes: cross sectional study

Objective To determine the prevalence of eating disorders in adolescent fem ales with type 1 diabetes mellitus compared with that in their non-diabetic peers. Design Cross sectional case-controlled study Setting Diabetes clinics and schools in three Canadian cities, Subjects 356 females aged 12-19 with type 1 diabetes and 1098 age matched n on-diabetic controls, Main outcome measure Eating disorders meeting Diagnos tic and Statistical Manual of Mental Disorders (DSM-IV) criteria. Results Eating disorders that met DSM-IV criteria were more prevalent in di abetic subjects (36, 10%) than in non-diabetic controls (49, 4%) (odds rati o 2.4, 95% confidence interval 1.5 to 3.7; P < 0.001). Subthreshold eating disorders were also more common in those with diabetes (49, 14%) than in co ntrols (84, 8%) (odds ratio 1.9, 95% confidence interval 1.3 to 2.8; P < 0. 001). Mean haemoglobin A(1c) concentration was higher in diabetic subjects with an eating disorder (9.4% (1.8)) than in those without (8.6% (1.6)), P = 0.04). Conclusions DSM-IV and subthreshold eating disorders are almost twice as co mmon in adolescent females with type 1 diabetes as in their non-diabetic pe ers, In diabetic subjects, eating disorders are associated with insulin omi ssion for weight loss and impaired metabolic control.