Synthesis of silenosterone, an insect-molting hormone

Authors
Mamadalieva, NZ Ramazanov, NS Saatov, Z
Citation
Nz. Mamadalieva et al., Synthesis of silenosterone, an insect-molting hormone, CHEM NAT CO, 35(6), 1999, pp. 653-655
Citations number
7
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
CHEMISTRY OF NATURAL COMPOUNDS
ISSN journal
00093130 → ACNP
Volume
35
Issue
6
Year of publication
1999
Pages
653 - 655
Database
ISI
SICI code
0009-3130(199911/12)35:6<653:SOSAIH>2.0.ZU;2-G
Abstract
Silenosterone is synthesized in five steps: acetylation of 2-desoxy-alpha-e cdysone (1), saponification of 2-desoxy-alpha-ecdysone-3,22-diacetate (2) t o the 22-monoacetate (3), and oxidation of the latter to a ketone (4) and i ts base hydrolysis (5). The structures of the compounds are confirmed by PM R, IR spectroscopy, and mass spectrometry.