Traceless linkers - Only disappearing links in solid-phase organic synthesis?

Traceless linkers, which enable the attachment of arenes and alkanes to a p olymeric support, have received increased attention in recent years. These anchoring groups allow chemical transformations on the polymer-bound molecu les, which can be cleaved from the resin leaving no residual functionality to bias the library. Various approaches based on different Group 14 to Grou p 16 heteroatoms have been developed in the past and used in new syntheses of diverse compound libraries.