Histopathological changes in gills of the estuarine crab Chasmagnathus granulata (Crustacea-Decapoda) following acute exposure to ammonia

Authors
Rebelo, MD Rodriguez, EM Santos, EA Ansaldo, M
Citation
Md. Rebelo et al., Histopathological changes in gills of the estuarine crab Chasmagnathus granulata (Crustacea-Decapoda) following acute exposure to ammonia, COMP BIOC C, 125(2), 2000, pp. 157-164
Citations number
18
Categorie Soggetti
Pharmacology & Toxicology
Journal title
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY
ISSN journal
13678280 → ACNP
Volume
125
Issue
2
Year of publication
2000
Pages
157 - 164
Database
ISI
SICI code
1367-8280(200002)125:2<157:HCIGOT>2.0.ZU;2-Z
Abstract
Histopathological effects of ammonia on the gills of the estuarine crab Cha smagnathus granulata (Dana, 1851) were evaluated after acute exposure to am monia concentrations around LC50 value (17.85 Mm). Disruption of Pilaster c ells and a subsequent collapse of gill lamellae were the main effects obser ved. Ephitelial necrosis and hyperplasia were also detected. Significant (P < 0.05) increases in pCO(2) and lactate, and significant decreases of pO(2 ) were detected in the haemolymph of ammonia-exposed crabs. These changes s uggest that the observed histopathological damage affected gas exchange, po ssibly leading to death. (C) 2000 Elsevier Science Inc. All rights reserved .