Multi-nephron and multi-vasa recta models of the inner medullary renal concentrating mechanism

Authors
Moon, IH Tewarson, RP
Citation
Ih. Moon et Rp. Tewarson, Multi-nephron and multi-vasa recta models of the inner medullary renal concentrating mechanism, COMPUT MATH, 40(2-3), 2000, pp. 345-357
Citations number
31
Categorie Soggetti
Computer Science & Engineering
Journal title
COMPUTERS & MATHEMATICS WITH APPLICATIONS
ISSN journal
08981221 → ACNP
Volume
40
Issue
2-3
Year of publication
2000
Pages
345 - 357
Database
ISI
SICI code
0898-1221(200007/08)40:2-3<345:MAMRMO>2.0.ZU;2-Q
Abstract
Three multi-nephron vasa recta models of the renal concentrating mechanism are presented. These models are physiologically more realistic than our shu nt vasa recta models. It is also shown that by considering the effects of f ractional transmural fluxes between tubes and role of the interstitium in t he permeability values, these models lead to significant improvements in co llecting duct urea and salt concentration ratios. (C) 2000 Elsevier Science Ltd. All rights reserved.