EFFECT OF SPACE-FLIGHT FACTORS ON PERIPHE RAL-BLOOD OF THE SPANISH NEWT

The effects of space flight factors (SFF) on the peripheral blood in P leurodeles waltlii were assessed after 12-day night on board of the bi osatellite <<Kosmos-2229>>. These animals were also used to study rege neration of the limb, tail and lens. The corresponding control groups of animals allowed to distinguish between the effects of the operation , non-specific and specific SFFs: (1) basal control - operated animals ; (2) synchronous control - operated animals kept on the Earth under t he same conditions as the flight group, and (3) intact animals. It has been shown that the relative content of neutrophils (mostly, young fo rms) increased and the proportion of lymphocytes and eosinophils decre ased under the influence of SFFs, while the capacity of blood cells fo r DNA synthesis was not affected. A conclusion has been drawn that the Spanish newts can be used for adequate studies of the SFF effects on the hemopoietic tissue.