SQUAMOUS-CELL CARCINOMA-LIKE AND POX LESIONS OCCURRING SIMULTANEOUSLYIN CHORIOALLANTOIC MEMBRANES OF CHICKEN EMBRYOS INOCULATED WITH MATERIALS FROM SQUAMOUS-CELL CARCINOMA AND POX LESIONS IN BROILER-CHICKENS

The finding of closely associated squamous cell carcinoma (SCC)-like l esions and pox lesions in chorioallantoic membranes (CAMs) inoculated with skin and palate samples taken from broilers is described. The sam ples were obtained from two broilers coming from different flocks that were not vaccinated against fowl pox. Both birds presented skin lesio ns, which were diagnosed in one bird as fowl pox, and in the other as SCC. After inoculation of CAMs with fresh tissues from both birds, his tologic examination revealed, in all CAMs, lesions that were character istic of fowl pox together with lesions consistent with those seen in the skin of broilers affected with SCC. This finding was unexpected an d may shed some light on the etiology of SCC.