Tm. Turpaev et Mv. Nechaeva, INVOLVEMENT OF NEUROTRANSMITTERS IN REGUL ATION OF THE MOTOR-ACTIVITYOF THE CHICK-EMBRYO AMNION, Izvestia Akademii nauk SSSR. Seria biologiceskaa, (4), 1994, pp. 686-693
The authors' data on time-related changes in the contractile activity
of non-innervated smooth muscle amnion of the chick embryo devoid of b
lood vessels and on involvement of the amniotic fluid neurotransmitter
s in regulation of the amnion motor activity have been summarized. A s
cheme of possible mechanism underlying regulation of the spontaneous r
hythmic contractile activity of the amnion by two antagonisfic neurotr
ansmitters present in the amniotic fluid: serotonin and noradrenalin,
which stimulate and inhibit the amnion motor activity, respectively. T
he results of experiments on successive block of the serotonin and adr
energic receptors by introduction of the corresponding antagonists in
the chick embryo amniotic fluid speak in favor of the proposed scheme
of humoral regulation of the amnion motor activity. A possible involve
ment of this humoral mechanism in the inhibitory effect of increased c
arbon dioxide content of the air on the amnion motor activity has been
considered.