Postpartum thyroiditis is the most common endocrinologic disorder, with an
incidence that varies geographically from 5% to 10%. It has important clini
cal sequelae including symptoms of hyperthyroidism, hypothyroidism, and dep
ression. Long-term follow-up of women who experience postpartum thyroiditis
reveals a high recurrence rate in subsequent pregnancies. Postpartum thyro
iditis is an autoimmune disorder, and thyroid antibody-positive women in th
e first trimester have a 33% to 50% chance of developing thyroiditis in the
postpartum period. Whether or not to screen for postpartum thyroiditis rem
ains controversial.