Dynamic contrast-enhanced MRI in the differentiation of breast tumors: User-defined versus semi-automated region-of-interest analysis

Dynamic contrast-enhanced MR mammography Is an increasingly used method of evaluating breast pathology. The purpose of this study was to compare two s emiautomated methods of region of interest (ROI) analysis with a user-defin ed method, in the discrimination of breast tumors using dynamic contrast-en hanced MRI. Results are presented from the retrospective analysis of 81 mal ignant and 36 benign breast lesions. The study demonstrates the importance of a consistent ROI strategy and also shows that semi-automated approaches offer a standardized method, which may improve the discrimination of primar y breast tumors, (C) 1999 Wiley-Liss, Inc.