Although magnetic resonance imaging (MRI) is capable of imaging various phy
siological parameters associated with the heart valves, it has generally be
en difficult to visualize the valve leaflets directly. The aortic valve was
imaged in 120 patients referred for cardiac MRI to assess myocardial volum
es or mass. The average patient age was 37 and ranged from 9 to 75 years, H
eart rate ranged from 43 to 100 bpm, Imaging was performed on a 1.5 T scann
er equipped with enhanced gradients and a cardiac phased-array coil, A doub
le inversion recovery fast spin-echo sequence was used to acquire short-axi
s images of the aortic valve in a breathhold (15 +/- 3 seconds). All three
leaflets of the aortic valve were seen in 102 of 120 studies (85%), Two lea
nets were detected in another 15 subjects. No leaflets were seen in three i
ndividuals. Seven cases of a bicuspid or thickened aortic valves were clear
ly distinguished from normal valves, The signal-to-noise ratio of aortic le
aflets (14 +/- 5) was significantly higher than that of the residual blood
signal in the aortic root (7 +/- 4, P < 0.001). MR images showed the aortic
valve leaflets in a high fraction of people with suspected normal aortic v
alves and detected seven cases of abnormal aortic valves. The potential of
MRI to study both the anatomic and functional consequences of valvular hear
t disease warrants further study. (C) 1999 Wiley-Liss, Inc.