Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects

Authors
Jander, G Rahme, LG Ausubel, FM
Citation
G. Jander et al., Positive correlation between virulence of Pseudomonas aeruginosa mutants in mice and insects, J BACT, 182(13), 2000, pp. 3843-3845
Citations number
23
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
182
Issue
13
Year of publication
2000
Pages
3843 - 3845
Database
ISI
SICI code
0021-9193(200007)182:13<3843:PCBVOP>2.0.ZU;2-F
Abstract
Strain PA14, a human clinical isolate of Pseudomonas aeruginosa, is pathoge nic in mice and insects (Galleria mellonella). Analysis of 32 different PA1 4 mutants in these two hosts showed a novel positive correlation in the vir ulence patterns. Thus, G. mellonella is a good model system for identifying mammalian virulence factors of P. aeruginosa.