Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar Typhimurium

Authors
Aguirre, A Lejona, S Vescovi, EG Soncini, FC
Citation
A. Aguirre et al., Phosphorylated PmrA interacts with the promoter region of ugd in Salmonella enterica serovar Typhimurium, J BACT, 182(13), 2000, pp. 3874-3876
Citations number
23
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
182
Issue
13
Year of publication
2000
Pages
3874 - 3876
Database
ISI
SICI code
0021-9193(200007)182:13<3874:PPIWTP>2.0.ZU;2-P
Abstract
The Salmonella PmrA-PmrB system controls the expression of genes necessary for polymyxin B resistance. Four loci were previously identified as part of the regulon, and interaction of PmrA with the promoter region of three of them was observed. Here we characterized the interaction of PmrA with the p romoter region of ugd, previously suggested to be regulated indirectly by P mrA. Our results indicate that PmrA controls the expression of ugd by inter acting with a specific sequence in the promoter region of this gene.