We describe a patient with polymorphic ventricular tachycardia (PVT)/ventri
cular fibrillation (VF) without organic heart disease who was cured by radi
ofrequency catheter ablation. The patient was a 65-year-old woman with a 10
-year history of recurrent syncope, There was no evidence of organic heart
disease, and the QT interval during sinus rhythm was borderline normal (cor
rected QT interval = 0.45 sec(1/2)). ECG recording during syncope showed PV
T, On one occasion, PVT degenerated into VF, This PVT was always induced by
a premature ventricular complex (PVC) originating from the right ventricul
ar (RV) outflow tract. Rapid pacing (220 beats/min) at the site of PVC orig
in reproduced polymorphic change of the QRS wave on surface ECG that was si
milar to PVT, This suggests that the PVT originated from a single focus in
the RV outflow tract. Catheter ablation was performed at the site of PVC or
igin. During 18-month follow-up, PVT/VF was not documented.