Synthesis of some 2,3 '-anhydro and 3 '-mesyl nucleosides

Authors
Abdel-Megied, AES
Citation
Aes. Abdel-megied, Synthesis of some 2,3 '-anhydro and 3 '-mesyl nucleosides, J CHEM R-S, (4), 2000, pp. 152-153
Citations number
16
Categorie Soggetti
Chemistry
Journal title
JOURNAL OF CHEMICAL RESEARCH-S
ISSN journal
03082342 → ACNP
Issue
4
Year of publication
2000
Pages
152 - 153
Database
ISI
SICI code
0308-2342(200004):4<152:SOS2'A>2.0.ZU;2-V
Abstract
The reaction of sugar 1 with silylated 5-alkoxymethyluracils 2a-c afforded 3a-c. Compounds 5a-c, 6a,b, 7a-c and 8c were prepared. Treatment of 4a,b wi th tris (1H-1,2,4-triazole-1-yl) phosphine oxide ana subsequent reaction wi th ammonia in dioxane, then with sodium methoxide yielded 9a,b.