Dc. Mohr et al., Telephone-administered cognitive-behavioral therapy for the treatment of depressive symptoms in multiple sclerosis, J CONS CLIN, 68(2), 2000, pp. 356-361
This study examined the efficacy of an 8-week telephone-administered cognit
ive-behavioral therapy (CBT) for the treatment of depressive symptomatology
in multiple sclerosis (MS) patients. The treatment, Coping with MS (CMS),
included a patient workbook designed to structure the treatment, provide vi
sual aids, and help with homework assignments. Thirty-two patients with MS,
who scored at least 15 on the Profile of Mood States Depression-Dejection
scale, were randomly assigned to either the telephone CMS or to a usual-car
e control (UCC) condition. Depressive symptomatology decreased significantl
y in the CMS condition compared with the UCC condition. Furthermore, adhere
nce to interferon beta-1a, a disease-modifying medication for the treatment
of MS, was significantly better at the 4-month follow-up among patients wh
o received CMS as compared with those in the UCC condition.