Small round structured viruses (SRSVs, Norwalk-like viruses, NLVs) are the
most common cause of outbreaks of gastro-enteritis in hospitals and also ca
use outbreaks in other settings such as schools, hotels, nursing homes and
cruise ships. Hospital outbreaks often lead to ward closure and major disru
ption in hospital activity. Outbreaks usually affect both patients and staf
f, sometimes with attack rates in excess of 50%. For this reason, staff sho
rtages can be severe, particularly if several wards are involved at the sam
e time. SRSVs may be spread by several routes: faecal-oral; vomiting/aeroso
ls; food and water. Viruses may be introduced into the ward environment by
any of these routes and then propagated by person-to-person spread. In an o
utbreak setting, the diagnosis can usually be made rapidly and confidently
on clinical and epidemiological grounds, particularly if vomiting is a prom
inent symptom. By the time an SRSV outbreak has been recognized at ward lev
el, most susceptible individuals will have been exposed to the virus and in
fection control efforts must prioritize the prevention of spread of infecti
on to other clinical areas by containment of infected/exposed individuals (
especially the prevention of patient and staff movements to other areas), h
and-hygiene and effective environmental decontamination.
This report of the Public Health Laboratory Service Viral Gastro-enteritis
Working Group reviews the epidemiology of outbreaks of infection due to SRS
Vs and makes recommendations for their management in the hospital setting.
The basic principles which underpin these recommendations will also be appl
icable to the management of some community-based institutional outbreaks. (
C) 2000 The Hospital Infection Society.