Influence of amphiphile concentration on the enantioselectivity in the rhodium-catalyzed reduction of unsaturated substrates in water

Authors
Robert, F Oehme, G Grassert, I Sinou, D
Citation
F. Robert et al., Influence of amphiphile concentration on the enantioselectivity in the rhodium-catalyzed reduction of unsaturated substrates in water, J MOL CAT A, 156(1-2), 2000, pp. 127-132
Citations number
20
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
ISSN journal
13811169 → ACNP
Volume
156
Issue
1-2
Year of publication
2000
Pages
127 - 132
Database
ISI
SICI code
1381-1169(20000520)156:1-2<127:IOACOT>2.0.ZU;2-W
Abstract
The enantioselectivity of the asymmetric hydrogenation of some unsaturated amino acid precursors with [Rh(COD)(1)]BF4 and [Rh(COD)(2)]ClO4 as catalyst is influenced by the presence of amphiphiles. Performing the reduction in water, both the activity and the enantioselectivity are enhanced significan tly in the presence of surfactants. The determination of the CMC of some su rfactants, as well as the reduction in mixtures of water/methanol in the pr esence of amphiphiles, give some evidence for the importance of micelles fo rmation in these enhancements. (C) 2000 Elsevier Science B.V. All rights re served.