Thioureas as new chiral ligands for the asymmetric hydroformylation of styrene with rhodium(I) catalysts

Authors
Breuzard, JAJ Tommasino, ML Touchard, F Lemaire, M Bonnet, MC
Citation
Jaj. Breuzard et al., Thioureas as new chiral ligands for the asymmetric hydroformylation of styrene with rhodium(I) catalysts, J MOL CAT A, 156(1-2), 2000, pp. 223-232
Citations number
31
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
ISSN journal
13811169 → ACNP
Volume
156
Issue
1-2
Year of publication
2000
Pages
223 - 232
Database
ISI
SICI code
1381-1169(20000520)156:1-2<223:TANCLF>2.0.ZU;2-O
Abstract
Various new chiral thioureas have been synthesized and used as ligands for the asymmetric hydroformylation of styrene catalyzed by rhodium(I) complexe s. The best results were obtained with N-phenyl-N'-(S)-(1-phenylethyl)-thio urea associated to a cationic rhodium(I) precursor, and asymmetric inductio n of 40% was then achieved. As enantioselectivity is obtained with low conv ersions, various parameters have been examined in order to increase the cat alytic activity without the loss of asymmetric induction. (C) 2000 Elsevier Science B.V. All rights reserved.