EFFECTS OF DIETS CONTAINING SEEDS OF GARCINIA-KOLA (HECKEL) ON GASTRIC-ACIDITY AND EXPERIMENTAL ULCERATION IN RATS

Authors
IBIRONKE GF OLALEYE SB BALOGUN O AREMU A
Citation
Gf. Ibironke et al., EFFECTS OF DIETS CONTAINING SEEDS OF GARCINIA-KOLA (HECKEL) ON GASTRIC-ACIDITY AND EXPERIMENTAL ULCERATION IN RATS, PTR. Phytotherapy research, 11(4), 1997, pp. 312-313
Citations number
9
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
11
Issue
4
Year of publication
1997
Pages
312 - 313
Database
ISI
SICI code
0951-418X(1997)11:4<312:EODCSO>2.0.ZU;2-L
Abstract
The antiulcerogenic and gastric acid lowering effects of Garcinia kola (Heckel) seeds were investigated in male albino rats, The animals wer e fed for 2 weeks on normal rat diets but specially composed to contai n 25%, 50% and 75% by weight of G. kola, It was observed that G. kola produced a dose-dependent inhibition of gastric acid secretion and ind omethacin-induced ulceration. We suggest that this might be due to its acid-lowering effect and increased mucus production among other facto rs yet to be determined. (C) 1997 by John Wiley & Sons, Ltd.