Ra. Tripp et al., Respiratory syncytial virus G and/or SH glycoproteins modify CC and CXC chemokine mRNA expression in the BALB/c mouse, J VIROLOGY, 74(13), 2000, pp. 6227-6229
Chemokine mRNA expression by pulmonary leukocytes following infection of BA
LB/c mice with two strains of respiratory syncytial virus (RSV) and one str
ain of parainfluenza virus type 3 (PIV-3) was determined. The results sugge
st that RSV G and/or SH proteins inhibit early MIP-1 alpha, MIP-1 beta, MIP
-2, MCP-1, and IP-10 mRNA expression. TCA-3 mRNA expression was found to be
increased during PIV-3 infection.