STABLE-ISOTOPE LABELING STUDIES ON THE BIOSYNTHESIS OF PINGUISANE-TYPE SESQUITERPENES IN AXENIC CULTURES OF ANEURA-PINGUIS

Authors
TAZAKI H SOUTOME H IWASAKI T NABETA K ARIGONI D
Citation
H. Tazaki et al., STABLE-ISOTOPE LABELING STUDIES ON THE BIOSYNTHESIS OF PINGUISANE-TYPE SESQUITERPENES IN AXENIC CULTURES OF ANEURA-PINGUIS, Chemical communications, (12), 1997, pp. 1101-1102
Citations number
11
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
12
Year of publication
1997
Pages
1101 - 1102
Database
ISI
SICI code
1359-7345(1997):12<1101:SLSOTB>2.0.ZU;2-R
Abstract
H-2 and C-13 NMR analyses of 6 alpha-hydroxy-3-oxopinguis-5(10)-ene-11 ,6-olide produced by axcenic cultures of the liverwort Aneura pinguis in the presence of H-2- and C-13-labelled mevalonates clarify the bios ynthesis of pinguisane-type sesquiterpenes from FPP via a 1,2-hydride shift, two 1,2-methyl shifts, a cleavage of the main FPP chain and the n recyclization.