SYNTHESIS OF MANOALIDE USING A 1,2-METALATE REARRANGEMENT

Authors
POMMIER A KOCIENSKI PJ
Citation
A. Pommier et Pj. Kocienski, SYNTHESIS OF MANOALIDE USING A 1,2-METALATE REARRANGEMENT, Chemical communications, (12), 1997, pp. 1139-1140
Citations number
15
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
12
Year of publication
1997
Pages
1139 - 1140
Database
ISI
SICI code
1359-7345(1997):12<1139:SOMUA1>2.0.ZU;2-1
Abstract
Manoalide, a marine antiinflammatory sesterterpenoid, has been synthes ised using a 1,2-metallate rearrangement of a higher order cuprate and a Pd-0-catalysed carbonylation of an iodo alkene to generate the cent ral dihydropyranone ring.