We show that estimates of the Lorentz symmetry violation extracted from ult
ra-high energy cosmic rays beyond the GZK cut-off set bounds on the paramet
ers of a Lorentz-violating extension of the Standard Model. Moreover, we ar
gue that correlated measurements of the difference in the arrival time of g
amma-ray photons and neutrinos emitted from Active Galactic Nuclei or Gamma
-Ray Bursts may provide a signature for a possible violation of the Lorentz
symmetry. We find that this time delay is energy independent, but that it
has a dependence on the chirality of the particles involved.