A study of the association between aneuploidy and fetal choroid plexus
cysts (CPCs) is presented. By reviewing the world prospective and ret
rospective studies, one cannot reach an agreed conclusion since differ
ent study designs were used and meta analysis is not feasible. Our exp
erience is that as a solitary ultrasonographic finding, genetic evalua
tion is not indicated in cases of CPC. However, all the 'risk factors'
of fetal aneuploidy such as maternal age, biochemical markers, and ul
trasonographic signs map create a score by which the indication for ge
netic evaluation will be more sound. (C) 1997 by John Wiley & Sons, Lt
d.