FETAL CHOROID-PLEXUS CYSTS - IS A GENETIC EVALUATION INDICATED

Authors
Citation
R. Sharony, FETAL CHOROID-PLEXUS CYSTS - IS A GENETIC EVALUATION INDICATED, Prenatal diagnosis, 17(6), 1997, pp. 519-524
Citations number
43
Categorie Soggetti
Obsetric & Gynecology
Journal title
ISSN journal
01973851
Volume
17
Issue
6
Year of publication
1997
Pages
519 - 524
Database
ISI
SICI code
0197-3851(1997)17:6<519:FCC-IA>2.0.ZU;2-M
Abstract
A study of the association between aneuploidy and fetal choroid plexus cysts (CPCs) is presented. By reviewing the world prospective and ret rospective studies, one cannot reach an agreed conclusion since differ ent study designs were used and meta analysis is not feasible. Our exp erience is that as a solitary ultrasonographic finding, genetic evalua tion is not indicated in cases of CPC. However, all the 'risk factors' of fetal aneuploidy such as maternal age, biochemical markers, and ul trasonographic signs map create a score by which the indication for ge netic evaluation will be more sound. (C) 1997 by John Wiley & Sons, Lt d.