The International Space Station will carry the external facility EXPOSE for
exobiological studies under free space conditions and/or selected space pa
rameters. Complementary to such experimentation in space, a profound ground
support program under simulated space conditions is required: (i) to suppo
rt the scientific EXPOSE community in the definition of the experiments und
er simulated space conditions; (ii) to determine the compatibility of the d
ifferent experiments (e.g., organics and biology); (iii) to optimize the ex
periments; (iv) to perform experiments sequence tests under simulated EXPOS
E environment conditions; (v) to run ground controls in parallel to the mis
sion; and (vi) for postflight analysis of phenomena observed in space. For
these laboratory studies, testbeds are available at DLR and GSF that simula
te the parameters of space, such as vacuum, solar electromagnetic and cosmi
c ionizing radiation, temperature extremes and reduced gravity that can be
applied separately, or in selected combinations. Such studies contribute to
answer several questions pertinent to exobiology, such as the relevance of
the delivery of extraterrestrial organic molecules to the Earth for the or
igin of life, the role of solar UV radiation in genetic stability, strategi
es of adaptation to environmental extremes, the probability and limits for
interplanetary transfer of life, and the needs for planetary protection. (C
) 2000 Elsevier Science Ltd. All rights reserved.