Certain medications, such as the phenothiazines, may cause side effects tha
t result in neck stiffness and may actually mimic the presentation of menin
gitis, especially in children. Despite the controversial use of antiemetics
, they continue to be used in children with viral gastroenteritis, I descri
be the case of a child who had a febrile seizure and meningismus during the
course of a viral gastroenteritis, not due to meningitis but to the untowa
rd side effect of an antiemetic, Clinicians must be aware that these medica
tions may cause extrapyramidal side effects that may mimic other more serio
us diseases and lead to unnecessary evaluations; therefore, their use canno
t be strongly encouraged. If antiemetics are prescribed, physicians should
emphasize possible side effects so that corrective treatment can be initiat
ed promptly.