The oxidized form of nicotinamide adenine dinucleotide

Authors
Guillot, B Jelsch, C Lecomte, C
Citation
B. Guillot et al., The oxidized form of nicotinamide adenine dinucleotide, ACT CRYST C, 56, 2000, pp. 726-728
Citations number
10
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
01082701 → ACNP
Volume
56
Year of publication
2000
Part
6
Pages
726 - 728
Database
ISI
SICI code
0108-2701(200006)56:<726:TOFONA>2.0.ZU;2-V
Abstract
The crystal structure of the free acid form of NAD(+) tetrahydrate (nicotin amide adenine dinucleotide tetrahydrate or 3-carbamoyl-1-beta-D-ribofuranos ylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate inner salt tetrahydrate, C21H27N7O14P2. 4H(2)O) has been determined at 100 K. NAD(+) i s the coenzyme of several protein families and plays a dominant role in bio logical redox processes. In this study, the molecule shows a different conf ormation from the one usually found in holoenzyme complexes.