Imaging transgenic animals

Citation
Tf. Budinger et al., Imaging transgenic animals, ANN REV B E, 1, 1999, pp. 611-648
Citations number
127
Categorie Soggetti
Multidisciplinary
Journal title
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING
ISSN journal
15239829 → ACNP
Volume
1
Year of publication
1999
Pages
611 - 648
Database
ISI
SICI code
1523-9829(1999)1:<611:ITA>2.0.ZU;2-M
Abstract
Transgenic and eugenic animals as small as 30 g can be studied noninvasivel y by radionuclides with resolutions of 1-2 mm, by MRT with resolution of 10 0 mu m and by light fluorescence and bioluminescence with high sensitivitie s. The technologies of radionuclide emission, magnetic resonance imaging, m agnetic resonance spectroscopy, optical tomography, optical fluorescence an d optical bioluminescence are currently being applied to small-animal studi es. These technologies and examples of their applications are reviewed in t his chapter.