Syntheses and antifilarial profile of 7-chloro-4-(substituted amino) quinolines: a new class of antifilarial agents

Authors
Tewari, S Chauhan, PMS Bhaduri, AP Fatima, N Chatterjee, RK
Citation
S. Tewari et al., Syntheses and antifilarial profile of 7-chloro-4-(substituted amino) quinolines: a new class of antifilarial agents, BIOORG MED, 10(13), 2000, pp. 1409-1412
Citations number
14
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960894X → ACNP
Volume
10
Issue
13
Year of publication
2000
Pages
1409 - 1412
Database
ISI
SICI code
0960-894X(20000703)10:13<1409:SAAPO7>2.0.ZU;2-#
Abstract
The syntheses of 7-chloro-4-(substituted amino) quinolines (2-22) and their antifilarial activities are delineated. Some of the screened compounds hav e shown promising filarial response and sterilization effect on female Acan thocheilonema viteae in rodents. (C) 2000 Elsevier Science Ltd. All rights reserved.