Self-measurement of blood pressure (SMBP) is increasingly used to assess bl
ood pressure outside the medical setting, A prerequisite for the wide use o
f SMBP is the availability of validated devices providing reliable readings
when they are handled by patients, This is the case today with a number of
fully automated oscillometric apparatuses, A major advantage of SMBP is th
e great number of readings, which is linked with high reproducibility, Give
n these advantages, one of the major indications for SMBP is the need for e
valuation of antihypertensive treatment, either for individual patients in
everyday practice or in clinical trials intended to characterize the effect
s of blood-pressure-lowering medications, In fact, SMBP is particularly hel
pful for evaluating resistant hypertension and detecting white-coat effect
in patients exhibiting high office blood pressure under antihypertensive th
erapy, SMBP might also motivate the patient and improve his or her adherenc
e to long-term treatment. Moreover, SMBP can be used as a sensitive techniq
ue for evaluating the effect of antihypertensive drugs in clinical trials;
it increases the power of comparative trials, allowing one to study fewer p
atients or to detect smaller differences in blood pressure than would be po
ssible with the office measurement, Therefore, SMBP can be regarded as a va
luable technique for the follow-up of treated patients as well as for the a
ssessment of antihypertensive drugs in clinical trials, (C) 2000 Lippincott
Williams & Wilkins.