Spectrophotometric determination of Fe(II) in multivitamin pharmaceutical preparations with 2-mercapto-5-(2,4-dihydroxy-5-carboxyphenylazo-1)-1,3,4-tiadiazole
S. Zareba et K. Szarwilo, Spectrophotometric determination of Fe(II) in multivitamin pharmaceutical preparations with 2-mercapto-5-(2,4-dihydroxy-5-carboxyphenylazo-1)-1,3,4-tiadiazole, CHEM ANAL, 45(3), 2000, pp. 449-453
The use of azo dye, namely 2-mercapto-5-(2,4-dihydroxy-5-carboxyphenylazo-1
)-1,3,4-tiadiazole (METIDAREZ-beta) was proposed for the spectrophotometric
determination of Fe(II) in the presence of other microelements as: Ca, Mg
(Vitamin 15 Solco); Ca, Co (Merz Spezial Dragees) and Ca, Co, Cu, Mn, K (Un
icap T) in the pharmaceutical multivitamin preparations. The results of the
spectrophotometric determinations were evaluated on statistically and comp
ared with the determinations by atomic absorption spectrometry (AAS). The a
dvantage of the presented method is its precision and reproducibility of th
e results.