The Frontal Lobe Score: part I: construction of a mental status of frontalsystems

Objective: To develop a bedside mental status examination to assess the beh avioural effects of damage to the frontal lobes. Design: A prospective clinical comparison of patients with cerebral lesions of different locations. Subjects: A total of 118 subjects were examined: 27 patients with cerebral lesions confined to the frontal lobes, 25 patients with cerebral lesions wi thout involvement of the frontal robes, 18 patients with mixed frontal/nonf rontal lesions, and 48 normal control subjects. Measures: Twenty-three mental status tests, clinical examinations and ratin g scales that had been reported as indicative of frontal robe function were brought together. By statistical analysis, 12 tests and a neurobehavioural rating scale were selected. These constitute the Frontal Lobe Score (FLS). Results: The FLS detected pure frontal lesions with a sensitivity of 77.7%. It discriminated patients with frontal lesions from normal control subject s with a specificity of 100%. Differentiation from patients with nonfrontal lesions was obtained with a specificity of 84%. Conclusion: The Frontal Lobe Score is a useful screening instrument for the clinical detection of effects of frontal lobe damage.