Citation
H. Sawada et al., Synthesis of a novel fluoroalkylated end-capped oligomer-bound antitumor segments and interaction of this oligomer with DNA, EUR POLYM J, 36(9), 2000, pp. 2051-2053
Citations number
11
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN POLYMER JOURNAL
ISSN journal
00143057
→ ACNP
Volume
36
Issue
9
Year of publication
2000
Pages
2051 - 2053
Database
ISI
SICI code
0014-3057(200009)36:9<2051:SOANFE>2.0.ZU;2-2
Abstract
New water-soluble fluoroalkylated end-capped co-oligomer-bound antitumor ag
ents such as 5-fluorouracil were prepared in good yields by the reaction of
the corresponding isocyanate-blocked co-oligomers with the parent antitumo
r agents under mild conditions and fluoroalkylated end-capped co-oligomer-b
ound 5-fluorouracil could have a remarkably strong interaction with DNA. (C
) 2000 Elsevier Science Ltd. All rights reserved.