Microwave-assisted, solventless Suzuki coupling reactions on palladium-doped alumina

The generation of carbon-carbon bonds forms the backbone of organic synthes is. In recent years, the use of boron-containing precursors in palladium-as sisted bond forming reactions (the Suzuki reaction) has gained prominence b ecause of the vast array of functionally substituted boron containing reage nts available to the organic chemist. The development of a solventless, mic rowave-assisted Suzuki reaction utilizing a readily recyclable solid cataly st offers numerous benefits. These include the straightforward recovery of both product and catalyst, conservation of energy through the use of microw ave irradiation, simple commercial scale up, and low waste protocols due to the absence of solvents.