A case control study was carried out in the Orthopaedic Department of Bradf
ord Royal Infirmary in an attempt to see if certain medical conditions, whi
ch can affect balance and stability, are more common in those who sustain a
second proximal femoral fracture. Medical conditions included in the study
were: late effects of cerebro-vascular accident, blindness, syncope and co
llapse, alcoholism Alzheimer's disease, epilepsy, Parkinsonism, ischaemic h
eart disease and senile dementia. The study group comprised 53 patients adm
itted to hospital between 1992 and 1998 with two separate proximal femoral
fractures each on a different side. The control group comprised 530 patient
s selected from a general pool of 2080 proximal femoral fracture patients a
dmitted to hospital during the same period. The control group patients were
matched to the study group for age, sex, and time of occurrence of the fir
st fracture. Results show significantly higher association of late effects
of cerebro-vascular accident, blindness, syncope and collapse, and Alzheime
r's disease with subsequent contralateral proximal femoral fractures. This
study supports a causal relationship between the above medical conditions a
nd subsequent contralateral proximal femoral fractures. It may therefore be
possible to identify patients who are at risk of returning with a second f
racture. (C) 2000 Elsevier Science Ltd. All rights reserved.