Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels

Citation
H. Masuoka et al., Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels, INTERN MED, 39(7), 2000, pp. 540-546
Citations number
30
Categorie Soggetti
General & Internal Medicine
Journal title
INTERNAL MEDICINE
ISSN journal
09182918 → ACNP
Volume
39
Issue
7
Year of publication
2000
Pages
540 - 546
Database
ISI
SICI code
0918-2918(200007)39:7<540:PVORPC>2.0.ZU;2-8
Abstract
Objective We designed the present study to evaluate the association of vari ous lipid and fibrinolytic components with coronary artery stenosis with re spect to the triglyceride (TG) level. Methods Levels of TG, remnant-like particle cholesterol (RLP-C), total chol esterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprot ein cholesterol (LDL-C). lipoprotein-(a), uric acid, blood glucose, tissue plasminogen activator (t-PA), t-PA inhibitor type 1, antithrombin III, and protein C were measured in 208 patients who underwent diagnostic coronary a ngiograms, Patients Of these 208 patients, 59 were hypertriglyceridemic (150 mg/dl or higher) and 139 were normotriglyceridemic, Results Both LDL-C and HDL-C showed significant differences between patient s with and those without coronary artery stenosis in both hypertriglyceride mic and normotriglyceridemic patient subgroups. However, RLP-C showed a sig nificant difference in the normotriglyceridemic patient subgroup (p=0,012) but not in the hypertriglyceridemic patient subgroup (p=0,736), Conclusion Our current retrospective study disclosed that RLP-C levels are closely associated with coronary artery stenosis in patients with normal TG levels.