H. Masuoka et al., Predictive value of remnant-like particle cholesterol as an indicator of coronary artery stenosis in patients with normal serum triglyceride levels, INTERN MED, 39(7), 2000, pp. 540-546
Objective We designed the present study to evaluate the association of vari
ous lipid and fibrinolytic components with coronary artery stenosis with re
spect to the triglyceride (TG) level.
Methods Levels of TG, remnant-like particle cholesterol (RLP-C), total chol
esterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprot
ein cholesterol (LDL-C). lipoprotein-(a), uric acid, blood glucose, tissue
plasminogen activator (t-PA), t-PA inhibitor type 1, antithrombin III, and
protein C were measured in 208 patients who underwent diagnostic coronary a
ngiograms,
Patients Of these 208 patients, 59 were hypertriglyceridemic (150 mg/dl or
higher) and 139 were normotriglyceridemic,
Results Both LDL-C and HDL-C showed significant differences between patient
s with and those without coronary artery stenosis in both hypertriglyceride
mic and normotriglyceridemic patient subgroups. However, RLP-C showed a sig
nificant difference in the normotriglyceridemic patient subgroup (p=0,012)
but not in the hypertriglyceridemic patient subgroup (p=0,736),
Conclusion Our current retrospective study disclosed that RLP-C levels are
closely associated with coronary artery stenosis in patients with normal TG
levels.